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DOTA peptides such as DOTATOC, DOTATATE, DOTA-NOC and others are being promoted for routine clinical use in nuclear medicine. what radionuclides are used to label the DOTA peptides for (a) diagnosis and (b) therapy and how are these supplied routinely? how are these radio-pharmaceuticals used clinically and what are their advantages? if available routinely they are likely to displace some of the raio-pharmaceuticals used currently-which ones? Do you think it would be cost-effective to change?

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