Folate, vitamin B6, vitamin B12, methionine and alcohol intake in relation to ovarian cancer risk

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1. Considering the Objective of the study and study design, was the method of dietary intake assessment valid and reliable? Why or why not?

2. In your opinion, what is the most important outcome of this study? Discuss why you think this is so.

3. The Authors discuss several strengths and limitations of their analysis. Are there any additional limitations not already mentioned? Of those limitations mentioned, are there any that severely impact the study quality?

4. Using the Quality Criteria Checklist (handed out in class and posted in the Course Documents fodler, QCC), how would your rate the quality of this study (+, – or 0), and what is the major reason for your quality grade?

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